Degenerative Myelopathy (DM) in German Shepherds
High Risk Category: Neurological Typical onset: 8-14 years Hereditary: Yes Est. treatment cost: £500-£3,000/year
Degenerative Myelopathy (DM) is one of the most frequently diagnosed conditions in the breed within the German Shepherd. Common indicators include progressive hind limb weakness, knuckling of hind paws, and dragging hind legs. DM is a progressive, non-painful spinal cord disease caused by a mutation in the SOD1 gene. It begins with hind limb weakness and ataxia, progressing to complete paralysis and eventually fore limb involvement. It is analogous to ALS in humans. It typically becomes apparent at 8-14 years. The large frame of the German Shepherd can accelerate progression in weight-bearing conditions, making early diagnosis particularly valuable. This condition has a hereditary component — prospective owners should request documentation of health screening from the breeder. Treatment costs are estimated at £500-£3,000/year, making comprehensive pet insurance a practical consideration.