Addison's Disease (Hypoadrenocorticism) is one of the most frequently diagnosed conditions in the breed within the Great Pyrenees. Common indicators include lethargy and weakness, vomiting and diarrhoea, and shaking. Addison's disease is caused by destruction of the adrenal cortex, leading to deficiency of glucocorticoids and mineralocorticoids. It can present as acute life-threatening 'Addisonian crisis' or with vague chronic signs that mimic many other conditions. It typically becomes apparent at 4-7 years. The giant frame of the Great Pyrenees can accelerate progression in weight-bearing conditions, making early diagnosis particularly valuable. This condition has a hereditary component — prospective owners should request documentation of health screening from the breeder. Treatment costs are estimated at £800-£2,500/year, making comprehensive pet insurance a practical consideration.
If your Great Pyrenees is showing any of these signs, consult your veterinarian promptly.
Acute crisis requires emergency IV fluids, dextrose, and corticosteroids. Maintenance involves lifelong monthly DOCP injections (mineralocorticoid) and daily prednisolone (glucocorticoid).
Estimated Treatment Cost
£800-£2,500/year
Costs vary by severity, location, and treatment path. Pet insurance is strongly recommended.
A diet formulation designed to support Great Pyreneess managing Addison's Disease (Hypoadrenocorticism). Formulated with high-quality protein and easily digestible ingredients.
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Great Pyreneess with Addison's Disease (Hypoadrenocorticism) benefit from consistent supplementation. This vet-formulated blend supports overall wellbeing and may complement prescribed treatment.
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Prevalence and severity can vary significantly between breeds.