Congenital Hypothyroidism with Goitre is a high-severity endocrine condition that can affect dogs of all ages and breeds. Congenital hypothyroidism with goitre is a hereditary disorder in which the thyroid gland fails to produce adequate thyroid hormone from birth due to a defect in thyroglobulin synthesis. Affected puppies are disproportionate dwarfs with severe growth retardation. It is documented across 2 breeds, though prevalence and severity can differ significantly between them. It typically becomes apparent at Birth. Early signs to watch for include disproportionate dwarfism, large head relative to body, short limbs, and goitre (enlarged thyroid). When treatment is required, costs are estimated at £300-£800/year depending on severity, location, and the specific intervention needed. Congenital Hypothyroidism with Goitre has a hereditary component, so health-screening certificates from the breeder are strongly recommended for predisposed breeds. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Congenital Hypothyroidism with Goitre in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

• Disproportionate dwarfism
• Large head relative to body
• Short limbs
• Goitre (enlarged thyroid)
• Mental dullness
• Lethargy

Treatment Overview

Lifelong thyroxine supplementation from the earliest age possible partially corrects the metabolic deficiency. Skeletal abnormalities cannot be reversed.

Typical onset: Birth

Prevention & Screening

While not all cases of Congenital Hypothyroidism with Goitre can be prevented, the following steps reduce risk or enable earlier intervention:

• DNA test available for Toy Fox Terriers and other affected breeds
• Do not breed affected or carrier animals together

Breeds Affected by Congenital Hypothyroidism with Goitre

The following 1 breed are documented as being susceptible to Congenital Hypothyroidism with Goitre. Click any breed to view breed-specific information about this condition, including prevalence and recommended screening.

• Spanish Water Dog (medium)