Exercise-Induced Collapse (EIC) is a medium-severity neurological condition that can affect dogs of all ages and breeds. EIC is a hereditary condition in Labrador Retrievers (and some related breeds) caused by a mutation in the dynamin-1 gene. Intense exercise causes episodes of collapse and incoordination, typically lasting 5-30 minutes, after which dogs fully recover. It is documented across 3 breeds, though prevalence and severity can differ significantly between them. It typically becomes apparent at 5 months - 3 years. Early signs to watch for include collapse after intense exercise, hind limb weakness and incoordination during episode, hyperthermia, and full recovery within 30 minutes. When treatment is required, costs are estimated at £100-£500 (management) depending on severity, location, and the specific intervention needed. Exercise-Induced Collapse (EIC) has a hereditary component, so health-screening certificates from the breeder are strongly recommended for predisposed breeds. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Exercise-Induced Collapse (EIC) in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

• Collapse after intense exercise
• Hind limb weakness and incoordination during episode
• Hyperthermia
• Full recovery within 30 minutes
• Dogs appear normal at rest

Treatment Overview

Avoidance of intense exercise is the primary management strategy. Affected dogs should not be used in high-drive activities. Most dogs can have normal quality of life with exercise modifications. Rare cases of severe episodes can be fatal.

Typical onset: 5 months - 3 years

Prevention & Screening

While not all cases of Exercise-Induced Collapse (EIC) can be prevented, the following steps reduce risk or enable earlier intervention:

• DNA test available — test all working Labradors before breeding
• Do not breed affected (EIC/EIC) dogs
• Exercise modification in carriers used for work

Breeds Affected by Exercise-Induced Collapse (EIC)

The following 4 breeds are documented as being susceptible to Exercise-Induced Collapse (EIC). Click any breed to view breed-specific information about this condition, including prevalence and recommended screening.

• Labrador Retriever (large)
• Chesapeake Bay Retriever (large)
• Curly-Coated Retriever (large)
• Boykin Spaniel (medium)