Hereditary Footpad Hyperkeratosis in Dogs

Moderate Risk Dermatological Hereditary

Hereditary Footpad Hyperkeratosis is a medium-severity dermatological condition that can affect dogs of all ages and breeds. Hereditary footpad hyperkeratosis causes excessive keratin production on the footpads from birth or early puppyhood, making the pads thickened, cracked, and painful. It significantly affects mobility and welfare if untreated. It is documented across 4 breeds, though prevalence and severity can differ significantly between them. It typically becomes apparent at Birth to 6 months. Early signs to watch for include thickened crusty footpads from puppyhood, foot pain and lameness, cracks and fissures in pads, and secondary bacterial infection. When treatment is required, costs are estimated at £200-£600/year depending on severity, location, and the specific intervention needed. Hereditary Footpad Hyperkeratosis has a hereditary component, so health-screening certificates from the breeder are strongly recommended for predisposed breeds. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Hereditary Footpad Hyperkeratosis in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

  • Thickened crusty footpads from puppyhood
  • Foot pain and lameness
  • Cracks and fissures in pads
  • Secondary bacterial infection
  • Reluctance to walk on hard surfaces

Treatment Overview

Regular soaking of footpads and removal of excess keratin, application of softening agents (petroleum jelly, propylene glycol), and boots to protect pads during walking. Antibiotics for infected fissures. Daily management is required.

Typical onset: Birth to 6 months

Prevention & Screening

While not all cases of Hereditary Footpad Hyperkeratosis can be prevented, the following steps reduce risk or enable earlier intervention:

  • DNA test available for Irish Terrier and Dogue de Bordeaux forms
  • Do not breed affected dogs

Estimated Treatment Cost

Treatment for Hereditary Footpad Hyperkeratosis is estimated at £200-£600/year, depending on severity, the specific intervention required, and your location. Costs may be higher for surgical procedures or ongoing management. Comprehensive pet insurance covering hereditary conditions is strongly recommended.

Breeds Affected by Hereditary Footpad Hyperkeratosis

The following 1 breed are documented as being susceptible to Hereditary Footpad Hyperkeratosis. Click any breed to view breed-specific information about this condition, including prevalence and recommended screening.

Looking for more information? Browse all dog health conditions or explore the health guides for in-depth breed care advice.