Histoplasma Infection is a high-severity gastrointestinal condition that can affect dogs of all ages and breeds. Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum, found in soil enriched with bird or bat droppings. Dogs in endemic areas (parts of North America) can develop respiratory and gastrointestinal forms. It is documented across 1 breed, though prevalence and severity can differ significantly between them. It typically becomes apparent at Any age. Early signs to watch for include weight loss, diarrhoea, anaemia, and respiratory distress. When treatment is required, costs are estimated at £1,500-£5,000 depending on severity, location, and the specific intervention needed. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Histoplasma Infection in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

• Weight loss
• Diarrhoea
• Anaemia
• Respiratory distress
• Lymphadenopathy
• Fever

Treatment Overview

Itraconazole is the first-line treatment for 4-6 months. Amphotericin B for severe cases. Prognosis depends on disease extent. Gastrointestinal histoplasmosis has a worse prognosis than respiratory form.

Typical onset: Any age

Prevention & Screening

While not all cases of Histoplasma Infection can be prevented, the following steps reduce risk or enable earlier intervention:

• Avoid known endemic areas with bird roost or bat cave exposure
• Do not allow dogs to dig in soil in endemic areas