Lymphoma is a high-severity cancer condition that can affect dogs of all ages and breeds. Canine lymphoma is one of the most common cancers in dogs, arising from lymphocytes in the lymph nodes, spleen, liver, or bone marrow. Multicentric (involving multiple lymph nodes) is the most common form. It is generally treatable but not curable. It is documented across 6 breeds, though prevalence and severity can differ significantly between them. It typically becomes apparent at 6-9 years. Early signs to watch for include swollen lymph nodes, weight loss, lethargy, and reduced appetite. When treatment is required, costs are estimated at £5,000-£12,000 depending on severity, location, and the specific intervention needed. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Lymphoma in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

• Swollen lymph nodes
• Weight loss
• Lethargy
• Reduced appetite
• Increased thirst and urination
• Vomiting

Treatment Overview

CHOP-based chemotherapy protocols achieve remission in 60-90% of dogs, with median survival of 12-14 months. Prednisolone alone provides short-term palliation. Targeted therapies are emerging.

Typical onset: 6-9 years

Prevention & Screening

While not all cases of Lymphoma can be prevented, the following steps reduce risk or enable earlier intervention:

• No proven prevention
• Annual health checks allow earlier detection

Breeds Affected by Lymphoma

The following 8 breeds are documented as being susceptible to Lymphoma. Click any breed to view breed-specific information about this condition, including prevalence and recommended screening.

• Golden Retriever (large)
• Boxer (large)
• Basset Hound (medium)
• Saint Bernard (giant)
• Scottish Terrier (small)
• Airedale Terrier (large)
• Vizsla (medium)
• Bullmastiff (giant)