Polycystic Kidney Disease (PKD) in Dogs

High Risk Urinary Hereditary

Polycystic Kidney Disease (PKD) is a high-severity urinary condition that can affect dogs of all ages and breeds. PKD is a hereditary condition characterised by multiple fluid-filled cysts in the kidneys that progressively replace normal renal tissue, leading to chronic kidney disease. A DNA test is available for the Bull Terrier form. It is documented across 3 breeds, though prevalence and severity can differ significantly between them. It typically becomes apparent at 3-7 years. Early signs to watch for include increased thirst and urination, weight loss, vomiting, and enlarged kidneys on palpation or ultrasound. When treatment is required, costs are estimated at £800-£3,000/year depending on severity, location, and the specific intervention needed. Polycystic Kidney Disease (PKD) has a hereditary component, so health-screening certificates from the breeder are strongly recommended for predisposed breeds. This page covers symptoms, treatment options, and preventive steps — along with breed-specific information where available.

Signs & Symptoms

The following symptoms are commonly associated with Polycystic Kidney Disease (PKD) in dogs. If your dog displays several of these signs, consult your vet promptly — early diagnosis typically leads to better outcomes.

  • Increased thirst and urination
  • Weight loss
  • Vomiting
  • Enlarged kidneys on palpation or ultrasound
  • Signs of renal failure in advanced disease

Treatment Overview

There is no cure. Management follows standard CKD protocols. Regular renal function monitoring and renal diet are used to slow progression.

Typical onset: 3-7 years

Prevention & Screening

While not all cases of Polycystic Kidney Disease (PKD) can be prevented, the following steps reduce risk or enable earlier intervention:

  • DNA test available for Bull Terrier form (ADPKD)
  • Ultrasound screening of breeding animals

Estimated Treatment Cost

Treatment for Polycystic Kidney Disease (PKD) is estimated at £800-£3,000/year, depending on severity, the specific intervention required, and your location. Costs may be higher for surgical procedures or ongoing management. Comprehensive pet insurance covering hereditary conditions is strongly recommended.

Breeds Affected by Polycystic Kidney Disease (PKD)

The following 3 breeds are documented as being susceptible to Polycystic Kidney Disease (PKD). Click any breed to view breed-specific information about this condition, including prevalence and recommended screening.

Looking for more information? Browse all dog health conditions or explore the health guides for in-depth breed care advice.